The Myers Cocktail is one of the best-known IV vitamin protocols in integrative medicine. Originally developed by Dr. John Myers, it combines B vitamins, magnesium, calcium and vitamin C to support energy, immunity and recovery.
What's in the Cocktail?
A standard Myers Cocktail contains magnesium chloride, calcium gluconate, B-complex (B1, B2, B3, B5, B6), B12 (methylcobalamin or hydroxocobalamin) and vitamin C — all diluted in sterile saline and infused intravenously over 30–60 minutes. Modern variations may add glutathione, taurine, zinc, selenium or amino acids depending on goal.
Who Benefits?
The Myers Cocktail is commonly used for fatigue, post-viral recovery, athletic recovery, migraine prophylaxis, fibromyalgia symptom relief, immune support before travel and the seasonal "wellness top-up" that many long-term patients use monthly. It is not a substitute for a healthy diet but provides high tissue concentrations of nutrients that the gut cannot absorb at equivalent doses orally.
The Session
The infusion takes 30–60 minutes in a comfortable seated position. Most patients feel an energy boost within hours; some notice deeper sleep on the night of the infusion. A single session can be enough for acute support; weekly sessions over 4–6 weeks are typical for chronic fatigue protocols.
Safety
Myers Cocktail is generally very well tolerated. A warm flush sensation as magnesium infuses is normal and resolves by slowing the drip. Caution is required in patients with severe renal impairment or known sensitivity to any component.
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